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Showing 641–656 of 1165 results
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Membrane Transporters: Methods and Protocols
Original price was: $169.00.$135.20Current price is: $135.20.Add to cartMembrane transporters and channels play key roles in drug absorption and distribution, influence drug efficacy and toxicity, and are the target of about 30% of currently marketed drugs. In Membrane Transporters: Methods and Protocols, a panel of recognized basic and clinical investigators-many world-famous-describe their proven, cutting-edge methodologies for studying these important proteins. Treated in step-by-step detail, these techniques take advantage of all the latest developments in biomedical research, including pharmacogenomics, bioinformatics, and microarray technologies. The authors explain databases and tools for bioinformatics analysis, provide practical guidelines for microarray experiments and data analysis, and illustrate the use of small-angle X-ray scattering, nuclear magnetic resonance (NMR), and molecular modeling to study the structural biology of membrane transporters. Methods for exploring structure-function correlation, such as site-directed mutagenesis, immunocytochemistry, and confocal microscopy, are also described, along with several methods that may help in the development of novel therapeutics. Each technique contains hands-on instructions, many notes on avoiding the problems that one may encounter, and suggestions for variant procedures.
Comprehensive and highly practical, Membrane Transporters: Methods and Protocols offers investigators working in biopharmaceutical science, drug discovery, and drug delivery both an array of powerful tools for work on membrane transporters and an essential guide to the state-of-the-art in the membrane transporter field today.
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Metallopharmaceuticals: DNA Interactions
Original price was: $349.00.$279.20Current price is: $279.20.Add to cartEach volume provides the reader, whether engaged in chemistry, biochemistry, biology or molecular medicine, with a comprehensive summary and critical overview of a topic of great current interest written by leading international experts.
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Metazoan Life without Oxygen
Original price was: $269.00.$215.20Current price is: $215.20.Add to cartMany multicellular animals do not require oxygen to live but respire anaerobically. Some of these have adapted to hostile environments, such as sulphide rich habitats, others live as parasites within host organisms, while others still can perhaps be said to look back on the early days of life on earth before anaerobic respiration had evolved.
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Methods in Aging Research
Original price was: $79.95.$63.96Current price is: $63.96.Add to cartGerontological research is currently of great interest due to ever-increasing longevity of human life spans. Created to provide researchers and scientists with the technical methods essential to their work, Methods in Aging Research is a practical bench-top guide for everyone who plans, designs, or conducts research in aging. It highlights experimental procedures that are key …
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Microbiology of Waterborne Diseases
Original price was: $235.00.$188.00Current price is: $188.00.Add to cartThis comprehensive text describes the diseases associated with water, their causative agents and the ways in which they gain access to water systems. It also details the methods for detecting and identifying waterborne microorganisms, the ways in which they are removed from water, and the risks they present to water users. This handbook will serve …
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Microscale Testing in Aquatic Toxicology
Original price was: $280.00.$224.00Current price is: $224.00.Add to cartBioassays are among the ecotoxicologist’s most effective weapons in the evaluation of water quality and the assessment of ecological impacts of effluents, chemicals, discharges, and emissions on the aquatic environment. Information on these assessment aids is needed throughout the international scientific and environmental management community. This comprehensive reference provides an excellent overview of the small-scale …
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Microwave Techniques and Protocols
Original price was: $179.00.$143.20Current price is: $143.20.Add to cartMicrowave technology can significantly reduce sample turnaround times, enhance quality, and reduce hazardous wastes when compared to bench or automated methods. In Microwave Techniques and Protocols, Richard Giberson and Richard Demaree, Jr., have collected a wide range of these time-saving techniques for processing biological samples for evaluation by many different microscopic methods.
Comprehensive and time saving, Microwave Techniques and Protocols demonstrates for anyone processing biological samples for immunocytochemistry, decalcification, and light or electron microscopy that microwave technology is a critically important tool in all experimental and clinical research laboratories today.
